HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isonicotinic Acid → HCID 67027000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isonicotinic Acid | HCID 5922 | — |
| Reactant | tert-Butyl 2,6-dichloropyridine-4-carboxylate | HCID 22594123 | — |
| Product | HCID 67027000 | HCID 67027000 | — |
Reaction Steps
2,6-Diisobutyl-isonicotinic acid hydrochloride is prepared starting from 2,6-dichloro-isonicotinic acid tert.-butyl ester and 2,4,6-tri-(2-methyl-propenyl)-cycloboroxane pyridine complex in analogy to isonicotinic acid 7; LC-MS: tR=0.68 min; [M+1]+=236.40; 1H NMR (D6-DMSO): δ 7.90 (s, 2H), 2.92 (d, J=6.3 Hz, 4H), 2.10 (hept, J=6.8 Hz, 2H), 0.90 (t, J=6.5 Hz, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580824B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-f62bb0decaf046b6ade36b2b93470bf6 |
| Source note | uspto-grants-2013_11 |