4-Hydroxy-2-methylbenzaldehyde → HCID 178458444, compound

HRID 2040790Notes

Reaction equation

HRID 2040790 reaction equation
[CH2:1]([O:4][C:5]1[C:14](C)=[CH:13][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[CH:7][C:6]=1CC)[CH:2]=[CH2:3].O[C:19]1C=CC(C=O)=C(C)C=1>>[CH2:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[C:13]([CH3:19])[CH:14]=1)[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 4581854-Hydroxy-2-methylbenzaldehydeHCID 178458381HCID 178458381, compound

Product 1

HCID 178458444HCID 178458444, compound

Procedure

The title compound is prepared in analogy to 4-allyloxy-3-ethyl-N-hydroxy-5-methyl-benzamidine starting from commercially available 4-hydroxy-2-methyl-benzaldehyde; LC-MS: tR=0.62 min, [M+1]+=207.10; 13C NMR (CDCl3): δ 20.72, 68.91, 104.72, 112.75, 116.45, 118.32, 118.53, 132.25, 134.19, 144.09, 161.71.

Sources & evidence

ORD record
ord-05c21fcc8731487685d3086c9fcb564e
Source dataset
uspto-grants-2013_11
Patent number
US08580824B2

Reaction notes

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