3-Chloro-4-hydroxy-5-methylbenzaldehyde → HCID 178458382, compound

HRID 2040792Notes

Reaction equation

HRID 2040792 reaction equation
[CH2:1]([O:4][C:5]1[C:14]([CH3:15])=[CH:13][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[CH:7][C:6]=1CC)[CH:2]=[CH2:3].[Cl:18]C1C=C(C=C(C)C=1O)C=O>>[CH2:1]([O:4][C:5]1[C:14]([CH3:15])=[CH:13][C:8]([C:9]([NH:11][OH:12])=[NH:10])=[CH:7][C:6]=1[Cl:18])[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 226613823-Chloro-4-hydroxy-5-methylbenzaldehydeHCID 178458381HCID 178458381, compound

Product 1

HCID 178458382HCID 178458382, compound

Procedure

The title compound is prepared in analogy to 4-allyloxy-3-ethyl-N-hydroxy-5-methyl-benzamidine starting from commercially available 3-chloro-4-hydroxy-5-methyl-benzaldehyde; LC-MS: tR=0.69 min, [M+1]+=241.10.

Sources & evidence

ORD record
ord-67a0bd4b1c304ae782e39d3210b3d478
Source dataset
uspto-grants-2013_11
Patent number
US08580824B2

Reaction notes

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