HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethyl-4-hydroxy-5-methyl-benzoic acid → 2-Ethyl-4-[3-(2-ethyl-6-methyl-pyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-6-methyl-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethyl-4-hydroxy-5-methyl-benzoic acid | HCID 59234777 | — |
| Reactant | HCID 178436634 | HCID 178436634 | — |
| Product | 2-Ethyl-4-[3-(2-ethyl-6-methyl-pyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-6-methyl-phenol | HCID 135964211 | — |
Reaction Steps
2-Ethyl-4-[3-(2-ethyl-6-methyl-pyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-6-methyl-phenol is prepared in analogy to Example 10 by coupling and cyclising 2-ethyl-N-hydroxy-6-methyl-isonicotinamidine with 3-ethyl-4-hydroxy-5-methyl-benzoic acid; LC-MS: tR=0.83 min; [M+1]+=324.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580824B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-dae0c3b1bfc24dba90e471a9d3ea0d2c |
| Source note | uspto-grants-2013_11 |