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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2040843Generated: November 2, 2026

1-(3-Nitropyridin-2-yl)piperidin-4-one → 6-Methyl-2-(4-methylene-1-piperidyl)-3-nitropyridine

https://huagongshe.com/reaction/2040843

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Nitropyridin-2-yl)piperidin-4-oneHCID 3510540—
Reactant2-(4-Methylene-1-piperidyl)-3-nitropyridineHCID 57493809—
Product6-Methyl-2-(4-methylene-1-piperidyl)-3-nitropyridineHCID 5749381062%

Reaction Steps

The title product was synthesized following the procedure reported for Compound 2a but replacing 1-(6-methyl-3-nitro-2-pyridyl)-4-oxopiperidine for 1-(3-nitro-2-pyridyl)-4-oxopiperidine. Yield: 62%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08580962B2
Source datasetuspto-grants-2013_11
ORD IDord-5bdab840fbff47e2b8504d4db0c215be
Source noteuspto-grants-2013_11