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HRID2040859

反应详情

EQUATION

反应方程式

HRID 2040859 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)N1CCC2(CC1)CC(O)(C#Cc1ccccc1)CO2
HCID57493817

未命名化合物

结构：CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)CCO2
HCID57493827

1-Oxa-9-azaspiro[5.5]undecane-9-carboxylic acid, 4-oxo-, 1,1-dimethylethyl ester

C14H23NO4

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC2(CC1)CC(O)(C#Cc1ccccc1)CCO2
HCID57493828

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the method reported here for Compound 26a, substituting ethyl 2-oxo-4-oxa-8-azaspiro[4.5]decane-8-carboxylate with Compound 29b. After the usual work-up procedure the oily residue was purified by means of automated flash chromatography (SP1®TM-Biotage; Petroleum Ether-EtOAc gradient 9:1 to 6:4) to give 0.96 g of the title compound as a grey solid. Yield: 57.3%

WORKUP

后处理

  1. customThe title compound was prepared
  2. customAfter the usual work-up procedure the oily residue was purified by means of automated flash chromatography (SP1®TM-Biotage; Petroleum Ether-EtOAc gradient 9:1 to 6:4)