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HRID2040910

反应详情

EQUATION

反应方程式

HRID 2040910 的结构方程式

REACTANTS

反应物

4
结构：CN=C=O
HCID12228

Methyl isocyanate

C2H3NO

结构：O=C(Cl)c1cccc(Cl)c1
HCID69252

Benzoyl chloride, 3-chloro-

C7H4Cl2O

结构：NC(=O)N1CCC2(CC(C#Cc3cccc(Cl)c3)=NO2)C1
HCID56644646

未命名化合物

结构：Clc1cccc(C#CC2=NOC3(CCNC3)C2)c1
HCID57493822

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1cccc(Cl)c1)N1CCC2(CC1)CC(C#Cc1cccc(Cl)c1)=NO2
HCID56644862

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized following the method herein described for the compound of Example 96 but replacing Compound 22c for Compound 27d and 3-chlorobenzoyl chloride for methyl isocyanate. After the usual work-up procedure the crude was purified by means of automated flash chromatography (Isolera®TM-Biotage; gradient Petroleum Ether-EtOAc from 8:2 to 6:4) giving 122 mg of the title compound a s a pale yellow oil. Yield: 67.5%.

WORKUP

后处理

  1. customThe title compound was synthesized
  2. customAfter the usual work-up procedure the crude was purified by means of automated flash chromatography (Isolera®TM-Biotage; gradient Petroleum Ether-EtOAc from 8:2 to 6:4)