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HRID2041353

反应详情

EQUATION

反应方程式

HRID 2041353 的结构方程式

REACTANTS

反应物

2
结构：Clc1ccc(CBr)nn1
HCID23080925

3-(Bromomethyl)-6-chloropyridazine

C5H4BrClN2

结构：CN(C)C(=O)Sc1c(Cl)ccc2c1CCN(C(=O)OC(C)(C)C)CC2
HCID57655979

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(Cl)nn3)c2CC1
HCID86629655

未命名化合物

PROCEDURE

实验过程

Use a method similar to the Preparation 177, using 3-tert-butoxycarbonyl-7-chloro-6-dimethylcarbamoylthio-2,3,4,5-tetrahydro-1H-benzo[d]azepine and 3-bromomethyl-6-chloropyridazine to give 3-tert-butoxycarbonyl-7-chloro-6-(6-chloro-pyridazin-3-ylmethylthio)-2,3,4,5-tetrahydro-1H-benzo[d]azepine. Use a method similar to the General Procedure 1-4 to give the title compound as an off-white powder. MS (APCI+) m/z: 340 (M+H)+.

WORKUP

后处理

  1. customsimilar to the Preparation 177