HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 55138441, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | m-Bromobenzenethiol | HCID 80597 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 55138441 | HCID 55138441 | 101% |
Reaction Steps
Add potassium hydroxide (4.89 g, 87.3 mmol) and 2-bromoacetophenone (15.8 g, 79.3 mmol) to a solution of 3-bromobenzenethiol (15 g, 79.3 mmol) in ethanol (200 mL, 70% in water) at 0° C. After stirring 16 h, add water to precipitate a yellow solid. Filter to obtain the desired intermediate (24.6 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580780B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a6edbe0429984d3aa72acea4f2877644 |
| Source note | uspto-grants-2013_11 |