Hydrochloric Acid → HCID 67194539, compound

Participants

Reaction Steps

(2S,4R)-1-Acetyl-6-bromo-2-methyl-1,2,3,4-tetrahydro-4-quinolinamine (for a preparation see intermediate 51) (4.24 g, 14.98 mmol) was dissolved in MeOH (20 mL) and the solution treated with HCl (1M in MeOH, 16.47 mL, 16.47 mmol). The resulting mixture was concentrated in vacuovacuo. The reside was co-evaporated with Et2O to give (2S,4R)-1-acetyl-6-bromo-2-methyl-1,2,3,4-tetrahydro-4-quinolinamine hydrochloride (4.255 g, 12.65 mmol, 84% yield) as a light brown solid.

Provenance & Evidence