HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Nitropyridin-2-yl)azetidin-3-ol → 1-(5-Aminopyridin-2-yl)azetidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Nitropyridin-2-yl)azetidin-3-ol | HCID 52937264 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 1-(5-Aminopyridin-2-yl)azetidin-3-ol | HCID 57431525 | 96.7% |
Reaction Steps
The process is carried out according to the method described in step 5.2, using 5.5 g (28.18 mmol) of 2-(3-hydroxyazetidin-1-yl)-5-nitropyridine, prepared in step 10.1, and 0.5 g of 10% palladium-on-charcoal. 4.5 g of the expected product are thus obtained in the form of violet crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586573B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-d26f75965f1a42c09c0bb89ff3a40d25 |
| Source note | uspto-grants-2013_11 |