Dichloromethane → N-(2-chloro-4-iodo-3-nitrophenyl)-3,3,3-trifluoro-2-methyl-2-trimethylsilyloxypropanamide

HRID 204207Notes

Reaction equation

HRID 204207 reaction equation
[C:13]([c:14]1[cH:15][cH:16][cH:17][c:18]([C:19]([CH3:20])([CH3:21])[CH3:22])[n:23]1)([CH3:24])([CH3:25])[CH3:26].[Cl:41][CH2:42][Cl:43].[F:27][C:28]([C:29]([C:30](=[O:31])[Cl:32])([CH3:33])[O:34][Si:35]([CH3:36])([CH3:37])[CH3:38])([F:39])[F:40].[I:1][c:2]1[c:3]([N+:10](=[O:11])[O-:12])[c:4]([Cl:9])[c:5]([NH2:6])[cH:7][cH:8]1>>[I:1][c:2]1[c:3]([N+:10](=[O:11])[O-:12])[c:4]([Cl:9])[c:5]([NH:6][C:30]([C:29]([C:28]([F:27])([F:39])[F:40])([CH3:33])[O:34][Si:35]([CH3:36])([CH3:37])[CH3:38])=[O:31])[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 685102,6-Di-tert-butylpyridineHCID 224988363,3,3-Trifluoro-2-methyl-2-trimethylsilyloxypropanoyl chlorideHCID 234394594-Iodo-3-nitro-2-chloroaniline

Product 1

HCID 23439400N-(2-chloro-4-iodo-3-nitrophenyl)-3,3,3-trifluoro-2-methyl-2-trimethylsilyloxypropanamide

Sources & evidence

ORD record
ord-349f584dbc8e451694bda663dc88659b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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