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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042148Generated: October 25, 2026

4-Ethynylpyridine → 2-tert-Butyl-6-pyridin-4-ylethynyl-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/2042148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthynylpyridineHCID 642801—
Reactant6-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidineHCID 58316697—
Product2-tert-Butyl-6-pyridin-4-ylethynyl-pyrazolo[1,5-a]pyrimidineHCID 53239666—

Reaction Steps

The title compound, white solid, MS: m/e=277.1 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 4-ethynylpyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586581B2
Source datasetuspto-grants-2013_11
ORD IDord-39780248d8ea4382ac4244aa122a793b
Source noteuspto-grants-2013_11