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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042161Generated: November 1, 2026

3-Bromopyrimidine → 2-tert-Butyl-6-pyrimidin-5-ylethynyl-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/2042161

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyrimidineHCID 20485635—
Reactant2-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidineHCID 58316702—
Product2-tert-Butyl-6-pyrimidin-5-ylethynyl-pyrazolo[1,5-a]pyrimidineHCID 53247331—

Reaction Steps

The title compound, light yellow solid, MS: m/e=278.2 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 3-bromopyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586581B2
Source datasetuspto-grants-2013_11
ORD IDord-8402e62e54e74fb6856cef7b1d95595b
Source noteuspto-grants-2013_11