Phenylacetylene → HCID 53247333, compound

HRID 2042164Notes

Reaction equation

HRID 2042164 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([CH:11]3[CH2:16][CH2:15][O:14][CH2:13][CH2:12]3)[CH:10]=2)[CH:7]=1.[C:17]1([C:23]#[CH:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:17]1([C:23]#[C:24][C:2]2[CH:3]=[N:4][C:5]3[N:6]([N:8]=[C:9]([CH:11]4[CH2:16][CH2:15][O:14][CH2:13][CH2:12]4)[CH:10]=3)[CH:7]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 10821PhenylacetyleneHCID 58316710HCID 58316710, compound

Product 1

HCID 53247333HCID 53247333, compound

Procedure

The title compound, grey solid, MS: m/e=304.1 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-(tetrahydro-pyran-4-yl)-pyrazolo[1,5-a]pyrimidine (example 26, step 2) and phenylacetylene.

Sources & evidence

ORD record
ord-2bd0535084564e9ca1fb15690c83a73e
Source dataset
uspto-grants-2013_11
Patent number
US08586581B2

Reaction notes

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