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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042165Generated: October 25, 2026

4-Ethynylaniline → 4-(2-tert-Butyl-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-phenylamine

https://huagongshe.com/reaction/2042165

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthynylanilineHCID 3760025—
Reactant6-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidineHCID 58316697—
Product4-(2-tert-Butyl-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-phenylamineHCID 53247334—

Reaction Steps

The title compound, brown solid, MS: m/e=291.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 4-ethynylaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586581B2
Source datasetuspto-grants-2013_11
ORD IDord-8e1759b1bd8a474e8df133f6683f2c1e
Source noteuspto-grants-2013_11