HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Difluoro-2-iodobenzene → 2-tert-Butyl-6-(2,5-difluoro-phenylethynyl)-pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Difluoro-2-iodobenzene | HCID 223084 | — |
| Reactant | 2-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine | HCID 58316702 | — |
| Product | 2-tert-Butyl-6-(2,5-difluoro-phenylethynyl)-pyrazolo[1,5-a]pyrimidine | HCID 53247455 | — |
Reaction Steps
The title compound, a white solid, MS: m/e=312.2 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 1,4-difluoro-2-iodobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586581B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-bd3692f4cd4b4e6a8c50b94f536680fc |
| Source note | uspto-grants-2013_11 |