HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethoxycarbonylphenylboronic acid → Ethyl 4-(2-chlorothieno[3,2-d]pyrimidin-7-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethoxycarbonylphenylboronic acid | HCID 2734350 | — |
| Reactant | 7-Bromo-2-chlorothieno(3,2-d)pyrimidine | HCID 56965724 | — |
| Product | Ethyl 4-(2-chlorothieno[3,2-d]pyrimidin-7-yl)benzoate | HCID 86673216 | 72% |
Reaction Steps
Ethyl 4-(2-chlorothieno[3,2-d]pyrimidin-7-yl)benzoate (185 mg, 72% yield) was prepared in the same manner as Step 6 of Example 1 using 7-bromo-2-chlorothieno[3,2-d]pyrimidine (200 mg, 0.81 mmol) and 4-(ethoxycarbonyl)phenylboronic acid (157 mg, 0.81 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-7782a415f3054a5d9257fff2bbf7bccd |
| Source note | uspto-grants-2013_11 |