HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Carboxyphenylboronic acid → 3-(2-Chlorothieno[3,2-d]pyrimidin-7-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Carboxyphenylboronic acid | HCID 2733957 | — |
| Reactant | 7-Bromo-2-chlorothieno(3,2-d)pyrimidine | HCID 56965724 | — |
| Product | 3-(2-Chlorothieno[3,2-d]pyrimidin-7-yl)benzoic acid | HCID 86673219 | 65.4% |
Reaction Steps
3-(2-Chlorothieno[3,2-d]pyrimidin-7-yl)benzoic acid (380 mg, 65% yield) was prepared in the same manner as Step 6 of Example 1 using 7-bromo-2-chlorothieno[3,2-d]pyrimidine (500 mg, 2.0 mmol) and 3-boronobenzoic acid (332 mg, 2.0 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-de5cda2836df4e9d823c360cc2d641ff |
| Source note | uspto-grants-2013_11 |