HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Carboxyphenylboronic acid → 3-(2-Aminothieno[3,2-d]pyrimidin-7-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Carboxyphenylboronic acid | HCID 2733957 | — |
| Reactant | 7-Bromothieno[3,2-d]pyrimidin-2-amine | HCID 67120137 | — |
| Product | 3-(2-Aminothieno[3,2-d]pyrimidin-7-yl)benzoic acid | HCID 67120145 | 56.3% |
Reaction Steps
3-(2-Aminothieno[3,2-d]pyrimidin-7-yl)benzoic acid (800 mg, 56% yield) was prepared in the same manner as Step 6 of Example 1 using 7-bromothieno[3,2-d]pyrimidin-2-amine (1.2 g, 5.24 mmol) and 3-boronobenzoic acid (870 mg, 5.24 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-ed2ccda147824e538f3748dc7995ba6a |
| Source note | uspto-grants-2013_11 |