HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide → 3-(2-aminothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide | HCID 57416240 | — |
| Reactant | 7-Bromothieno[3,2-d]pyrimidin-2-amine | HCID 67120137 | — |
| Product | 3-(2-aminothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide | HCID 67120139 | 64.6% |
Reaction Steps
3-(2-Aminothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide (180 mg, 64% yield) was prepared in the same manner as Step 6 of Example 1 using 7-bromothieno[3,2-d]pyrimidin-2-amine (200 mg, 0.87 mmol) and N-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (260 mg, 0.87 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-03bc8e297a0e43a989039225faf825a6 |
| Source note | uspto-grants-2013_11 |