HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Morpholino)pyridin-3-amine → N2-(6-Morpholinopyridin-3-yl)-N7-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-2,7-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Morpholino)pyridin-3-amine | HCID 104059 | — |
| Reactant | 2-chloro-N-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-7-amine | HCID 86673224 | — |
| Product | N2-(6-Morpholinopyridin-3-yl)-N7-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-2,7-diamine | HCID 52932125 | 74.5% |
Reaction Steps
N2-(6-Morpholinopyridin-3-yl)-N7-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-2,7-diamine (21 mg, 74% yield) was prepared in the same manner as Step 10 of Example 1 using 2-chloro-N-(3,4,5-trimethoxyphenyl)thieno[3,2-d]pyrimidin-7-amine (20 mg, 0.057 mmol) and 6-morpholinopyridin-3-amine (12 mg, 0.068 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586580B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-fc77797d8716401d9aeba9cc21a09542 |
| Source note | uspto-grants-2013_11 |