HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperazin-1-yl)thieno[3,2-c]pyridine → HCID 178474980, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperazin-1-yl)thieno[3,2-c]pyridine | HCID 10966027 | — |
| Reactant | HCID 178474986 | HCID 178474986 | — |
| Product | HCID 178474980 | HCID 178474980 | — |
Reaction Steps
The title compound, light brown solid (114 mg, 43%), MS (ISP) m/z=387.1 [(M+H)+], was prepared in analogy to example 1 from commercially available 4-piperazine-1-yl-thieno[3,2-c]pyridine [CAS-Nr. 106261-27-2] (150 mg, 0.68 mmol) and trans-N-[4-(2-oxo-ethyl)-cyclohexyl]-acetamide [CAS-Nr. 946599-01-5, WO 2007/093540] (125 mg, 0.68 mmol). Purification was performed by flash chromatography over silica gel (CH2Cl2/MeOH/25% NH3 aq 140:10:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586579B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-06b2081d3a0d4e7da50b500e7556f208 |
| Source note | uspto-grants-2013_11 |