HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178478593, compound → HCID 178496558, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178478593 | HCID 178478593 | — |
| Reactant | HCID 178496559 | HCID 178496559 | — |
| Product | HCID 178496558 | HCID 178496558 | — |
Reaction Steps
The title compound was prepared in analogy to example 4 starting from trans-4-[2-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine trihydrochloride (intermediate B) (100 mg, 0.22 mmol) and (trans-4-methoxy-cyclohexyl)-acetic acid [CAS-Nr. 879877-61-9, US 2010/075985] (40 mg, 0.23 mmol). Purification by flash chromatography on silica gel (CH2Cl2/MeOH 95:5). White crystals (68 mg, 62%), MS (ISP) m/z=499.3 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586579B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-7fd5d6631deb48c085bedf0f8ad9d5ac |
| Source note | uspto-grants-2013_11 |