Racemic trans-(3-methoxy-cyclopentyl)-acetic acid methyl ester → HCID 178496557, compound

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The title compound was prepared in analogy to example 2 starting from trans-4-[2-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-ethyl]-cyclohexylamine trihydrochloride (intermediate B) (100 mg, 0.22 mmol) and racemic trans-(3-methoxy-cyclopentyl)-acetic acid methyl ester [WO 2009/019174] (46 mg, 0.27 mmol). Purification by flash chromatography on silica gel (CH2Cl2/MeOH 95:5). White crystals (61 mg, 57%), MS (ISP) m/z=485.4 [(M+H)+].

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