2-Methanesulfonylacetic acid → HCID 178504901, compound

Participants

Reaction Steps

The title compound, off-white solid (106 mg, 78%), MS (ISP) m/z=451.3 [(M+H)+], mp 260.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (132 mg, 0.3 mmol) and 2-methylsulfonyl-acetic acid.

Provenance & Evidence