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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042449Generated: October 30, 2026

Cyclobutanecarboxylic acid → HCID 178523692, compound

https://huagongshe.com/reaction/2042449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarboxylic acidHCID 19494—
ReactantHCID 178478589HCID 178478589—
ProductHCID 178523692HCID 178523692—

Reaction Steps

The title compound, white solid (77 mg, 75%), MS (ISP) m/z=413.5 [(M+H)+], mp 202° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and cyclobutanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586579B2
Source datasetuspto-grants-2013_11
ORD IDord-2824d3dc90a74d56bfe6d58ea98086aa
Source noteuspto-grants-2013_11