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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042451Generated: November 5, 2026

4-(Piperidin-1-yl)benzoic acid → HCID 178523703, compound

https://huagongshe.com/reaction/2042451

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-1-yl)benzoic acidHCID 764599—
ReactantHCID 178478589HCID 178478589—
ProductHCID 178523703HCID 178523703—

Reaction Steps

The title compound, off-white solid (100 mg, 77%), MS (ISP) m/z=518.5 [(M+H)+], mp 214.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 4-piperidin-1-yl-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586579B2
Source datasetuspto-grants-2013_11
ORD IDord-617a2c2faf084de6bf8c0d1b5a24cd2a
Source noteuspto-grants-2013_11