HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxy-1-cyclopropanecarboxylic acid → HCID 178523714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxy-1-cyclopropanecarboxylic acid | HCID 2733160 | — |
| Reactant | HCID 178478589 | HCID 178478589 | — |
| Product | HCID 178523714 | HCID 178523714 | — |
Reaction Steps
The title compound, off-white solid (41 mg, 40%), MS (ISP) m/z=415.4 [(M+H)+], mp 174.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 1-hydroxy-cyclopropanecarboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586579B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-06abae43f787486695013b518e50aa45 |
| Source note | uspto-grants-2013_11 |