3-Bromobenzene-1-sulfonamide → 3-[5-(4-Chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

HRID 204246Notes

Reaction equation

HRID 204246 reaction equation
[Br:23][c:24]1[cH:25][c:26]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:27][cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[CH:22])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[C:22][c:24]2[cH:25][c:26]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:27][cH:28][cH:29]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 27347653-Bromobenzene-1-sulfonamideHCID 866079955-(4-Chloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 118527223-[5-(4-Chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-f40218f34d84431194da85e9cf4be2c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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