2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → HCID 178425864, compound

Participants

Reaction Steps

The title compound, white solid (68 mg, 75%), MS (ISP) m/z=454.4 [(M+H)+], mp 172.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and 2-(3-methylisoxazol-5-yl)-acetic acid.

Provenance & Evidence