N,N-Dimethylsuccinamic acid → HCID 178484544, compound

Participants

Reaction Steps

The title compound, white solid (48 mg, 52%), MS (ISP) m/z=458.6 [(M+H)+], mp 188° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and 4-(dimethylamino)-4-oxobutanoic acid.

Provenance & Evidence