3-Hydroxyisovaleric acid → HCID 178459210, compound

Participants

Reaction Steps

The title compound, off-white solid (68 mg, 79%), MS (ISP) m/z=431.6 [(M+H)+], mp 208° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and 3-hydroxy-3-methyl-butanoic acid.

Provenance & Evidence