Methyl (S)-3-hydroxypentanoate → HCID 178456103, compound

Participants

Reaction Steps

The title compound, white solid (66 mg, 77%), MS (ISP) m/z=431.4 [(M+H)+], mp 158° C., was prepared in accordance with the general method of example 2 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and (S)-methyl 3-hydroxy-pentanoate.

Provenance & Evidence