4,4,4-Trifluorobutanoic acid → HCID 178520633, compound

Participants

Reaction Steps

The title compound, white solid (53 mg, 58%), MS (ISP) m/z=455.4 [(M+H)+], mp 195.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and 4,4,4-trifluoro-butanoic acid.

Provenance & Evidence