Oxane-4-carboxylic acid → HCID 178430612, compound

Participants

Reaction Steps

The title compound, white solid (60 mg, 88%), MS (ISP) m/z=457.5 [(M+H)+], mp 223.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(7-methyl-2,3-dihydro-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate G) (68.1 mg, 0.15 mmol) and tetrahydropyran-4-yl-carboxylic acid.

Provenance & Evidence