Methyl 3,3-dimethoxypropionate → HCID 178495582, compound

Participants

Reaction Steps

The title compound, white solid (101 mg, 91%), MS (ISP) m/z=447.4 [(M+H)+], mp 220° C., was prepared in accordance with the general method of example 2 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and methyl 3,3-dimethoxy-propanoate.

Provenance & Evidence