Benzo-1,3-dioxole-5-acetic acid → HCID 178520186, compound

Participants

Reaction Steps

The title compound, white solid (110 mg, 89%), MS (ISP) m/z=493.4 [(M+H)+], mp 212° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 2-(benzo[1,3]dioxol-5-yl)-acetic acid.

Provenance & Evidence