6-Quinolinecarboxylic acid → HCID 178523694, compound

Participants

Reaction Steps

The title compound, off-white solid (120 mg, 99%), MS (ISP) m/z=486.4 [(M+H)+], mp 227° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and quinoline-6-carboxylic acid.

Provenance & Evidence