2-(1,2-Benzoxazol-3-yl)acetic acid → HCID 178520400, compound

Participants

Reaction Steps

The title compound, white solid (114 mg, 93%), MS (ISP) m/z=490.4 [(M+H)+], mp 217.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 2-benzo[d]isoxazol-3-yl-acetic acid.

Provenance & Evidence