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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042518Generated: November 2, 2026

5-(Morpholin-4-yl)pyrazine-2-carboxylic acid → HCID 178523713, compound

https://huagongshe.com/reaction/2042518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Morpholin-4-yl)pyrazine-2-carboxylic acidHCID 45789762—
ReactantHCID 178478589HCID 178478589—
ProductHCID 178523713HCID 178523713—

Reaction Steps

The title compound, white solid (107 mg, 82%), MS (ISP) m/z=522.5 [(M+H)+], mp 192.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 5-morpholin-4-yl-pyrazine-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586579B2
Source datasetuspto-grants-2013_11
ORD IDord-d363b4a135a2460297e826587cf8da0e
Source noteuspto-grants-2013_11