4-tert-Butylbenzoic acid → HCID 178440971, compound

Participants

Reaction Steps

The title compound, white solid (80 mg, 65%), MS (ISP) m/z=491.5 [(M+H)+], mp 186.5° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 4-tert-butyl-benzoic acid.

Provenance & Evidence