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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042522Generated: November 2, 2026

(1,1'-Biphenyl)-4-carboxylic acid → HCID 178523695, compound

https://huagongshe.com/reaction/2042522

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReactantHCID 178478589HCID 178478589—
ProductHCID 178523695HCID 178523695—

Reaction Steps

The title compound, white solid (93 mg, 73%), MS (ISP) m/z=511.6 [(M+H)+], mp 232° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and biphenyl-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586579B2
Source datasetuspto-grants-2013_11
ORD IDord-988c22747adb4055854137174ea8ec39
Source noteuspto-grants-2013_11