4-tert-Butoxybenzoic Acid → HCID 178450180, compound

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Reaction Steps

The title compound, white solid (82 mg, 65%), MS (ISP) m/z=507.3 [(M+H)+], mp 200° C., was prepared in accordance with the general method of example 32 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and 4-tert-butoxy-benzoic acid.

Provenance & Evidence