(-)-Methyl (R)-3-hydroxyvalerate → HCID 178456102, compound

Participants

Reaction Steps

The title compound, white solid (58 mg, 54%), MS (ISP) m/z=431.5 [(M+H)+], mp 161° C., was prepared in accordance with the general method of example 2 from trans-4-{2-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yl)-piperazin-1-yl]-ethyl}-cyclohexanamine trihydrochloride (intermediate C) (110 mg, 0.25 mmol) and methyl (R)-3-hydroxy-pentanoate.

Provenance & Evidence