Boron tribromide → HCID 135982272, compound

Participants

Reaction Steps

A solution of the product from step 2 (1.0 g, 3.3 mmol) in 25 mL of CH2Cl2 was cooled to 0° C. and BBr3 (1M in DCM, 16.7 mL) was added dropwise. The ice-bath was removed and the reaction was stirred at rt for 1 h. The reaction mixture was then poured into 50 mL of ice cold saturated NH4Cl solution with stirring. The resulting solid was collected, washed with water (3×15 mL), and Et2O (2×15 mL) to give the product of step 3 (868 mg, 92%): Mp 256-257° C.; MS m/z 287 (M+H).

Provenance & Evidence