HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042546Generated: November 2, 2026
6-Methoxy-alpha-tetralone → HCID 59651944, compound
https://huagongshe.com/reaction/2042546
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 6-Methoxy-alpha-tetralone | HCID 14112 | — |
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 59651944 | HCID 59651944 | 30% |
Reaction Steps
A mixture of 6-methoxy-1-tetralone (20 g, 114 mmol) and glyoxylic acid monohydrate (10.5 g, 114 mmol) was heated at 120° C. in a melt for 5 min. After slight cooling, EtOAc (100 mL) was carefully added. The solid which precipitated was collected to afford 8.5 g (30%) of hydroxyl-(6-methoxy-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetic acid; Mp 212-214° C., MS m/z 251 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08586588B2 |
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| Source dataset | uspto-grants-2013_11 |
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| ORD ID | ord-a42fa2d9ba164a90b005ed2bd79efcf5 |
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| Source note | uspto-grants-2013_11 |
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