Piperidine-1-propanol → HCID 24993173, compound
Reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH2:9][CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][CH:3]=1.[N:15]1([CH2:21][CH2:22][CH2:23][OH:24])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[N:15]1([CH2:21][CH2:22][CH2:23][O:24][C:2]2[N:7]=[CH:6][C:5]([C:8]3[CH:9]=[CH:10][C:11](=[O:14])[NH:12][N:13]=3)=[CH:4][CH:3]=2)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1Participants
3
Procedure
This compound was prepared using the intermediate from step 1 example 139 and 3-piperidin-1-yl-propanol using methods described for example 146; Mp 155-158° C. MS m/z 315 (M+H).
Workup
- customThis compound was prepared
Sources & evidence
- ORD record
- ord-50a7125f4efb45e292a070675883661b
- Source dataset
- uspto-grants-2013_11
- Patent number
- US08586588B2
Reaction notes
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