indium(III)chloride → HCID 178515844, 화합물

HRID 2042746노트

반응식

HRID 2042746 반응식
[Cl-].[In+3].[Cl-].[Cl-].O1[C:9]2([CH2:14][CH2:13][CH:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[CH:25]=[C:24]([O:26][CH2:27][C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=5[O:34][C:35]([F:38])([F:37])[F:36])[NH:23][N:22]=4)=[CH:17][N:16]=3)[CH2:11][CH2:10]2)[O:8]CC1>CO.O>[F:38][C:35]([F:36])([F:37])[O:34][C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=1[CH2:27][O:26][C:24]1[NH:23][N:22]=[C:21]([C:18]2[CH:19]=[CH:20][C:15]([CH:12]3[CH2:13][CH2:14][C:9](=[O:8])[CH2:10][CH2:11]3)=[N:16][CH:17]=2)[CH:25]=1

참가 물질

5

반응물 2

HCID 159675indium(III)chlorideHCID 178506374HCID 178506374, 화합물

생성물 1

HCID 178515844HCID 178515844, 화합물

시약·촉매·용매 2

HCID 887Methanol용매2회HCID 962Water용매

실험 절차

Indium chloride (0.11 g, 0.536 mmol) was added to a solution of Example 93E (0.255 g, 0.536 mmol) in methanol (3 ml) and water (3 mL). The resulting solution was heated (85° C.) for hours before the methanol was evaporated. The residue was partitioned with ethyl acetate and water, and the organic phase was washed with brine, dried (magnesium sulfate), filtered, and concentrated. The crude product was used in the following step without further purification.

후처리

  1. customwas evaporated
  2. customThe residue was partitioned with ethyl acetate and water
  3. washthe organic phase was washed with brine
  4. dry with materialdried (magnesium sulfate)
  5. filtrationfiltered
  6. concentrationconcentrated
  7. customThe crude product was used in the following step without further purification

출처 및 근거

ORD 기록
ord-7a77301a199146a69d2382662e21ab7c
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08586594B2

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