反应详情

温度

50 °C

Approx. 50 mg of 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate anhydrate in its crystalline modification A1 were dispersed in approx. 0.15 mL of a binary mixture DI water/acetonitrile (1:1, v/v), and shaken as slurry at 50° C. at 1000 rpm for 7 days. The dispersion was then filtered and resulting crystals were dried at ambient conditions on the filter.

1. filtrationThe dispersion was then filtered
2. customresulting crystals
3. customwere dried at ambient conditions on the filter